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MCAT Organic Question — Silica Plates

  • by John
  • Jul 14, 2017
  • MCAT Question of the Day

Which compound will migrate the fastest during thin layer chromatography using silica plates?

 

silica plates

Click for Explanation
During thin layer chromatography on silica plates, polar molecules are attracted to the silica and migrate slower than non-polar compounds. Of the answer choices, only cyclohexane is non-polar. Choice A is correct.

 

A. Correct.

B. Incorrect, ketone group makes this molecule polar.

C. Incorrect, the carboxylic acid group is polar.

D. Incorrect, the alcohol is polar.

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