Caudal-related homeobox gene 2 (CDX2) is expressed early in embryonic development and is essential for the proper development of the intestines. Later in development, CDX2 is expressed in intestinal epithelial stem cells, which differentiate into cells that form the epithelial lining of the intestines. Which germ layer would be expected to have the most robust expression of this gene?
I. Endoderm
II. Mesoderm
III. Ectoderm
A. I only
B. II only
C. III only
D. I and II
Click for Explanation
The epithelial lining of the gastrointestinal tract, liver, gallbladder, and pancreas originates from the endoderm.
A. I only, Correct
B. II only
C. III only
D. I and II
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