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PCAT Biological Processes – Enzyme Digestion of Macronucrients

Which of the following correctly matches the macronutrient with the location of digestion by digestive enzymes?

A. Disaccharides—small intestine
B. Proteins—pancreas
C. Disaccharides—mouth
D. All of the above are correct.

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A is correct. Disaccharides, including sucrose and lactose, are broken down in the small intestine by enzymes known as disaccharidases. The pancreas is the source of the zymogen form of trypsin, a protease, but proteins are not actually digested in the pancreas. Finally, starch is partially digested in the mouth by salivary amylase, but starch is a polysaccharide, not a disaccharide.

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