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A: While reaction 1 is peptide bond formation, the reverse reaction is not an addition reaction. In addition reactions two molecules combine. Here, reaction 2 shows one large molecule being broken down.
C: These are the right labels, but applied backwards.
D: Reaction 2 is hydrolysis, but reaction 1 is not a nucleophilic addition; it’s a substitution reaction. The OH group is being substituted for the amino group of the amino acid on the right. Thus, this is a nucleophilic acyl substitution.
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