Synthesis of intracellular proteins is initiated at which of the following sites?
- Free-standing ribosomes
- Rough endoplasmic reticulum
- Golgi apparatus
- I only
- II only
- I and II
- I, II, and III
Click for Explanation
- True. Translation of intracellular proteins is always initiated on free-free standing ribosomes in the cytosol.
- False. Proteins that are destined for secretion are translated on ribosomes bound to the rough endoplasmic reticulum, but proteins with an intracellular destination are synthesized on free ribosomes.
- False. The Golgi apparatus is responsible for packaging proteins that are to be secreted by the cell.
Answer: A. See explanations above.
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