BLUEPRINT MCAT BLOG

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MCAT Organic Question — SDS-PAGE Procedure

In an SDS-PAGE procedure, the SDS serves as a detergent. Why are the proteins treated with a detergent before being run through the electrophoresis gel?   A. To coat the proteins with a large positive charge, since amino acid side chains may have positive, negative, or neutral charges, and a large uniform charge is necessary

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